We found positive correlations between ACC, KIRC, THCA, COAD, COADREAD, OV, PAAD, GBM, and other tumors in m1A-, m5C-, and m6A-related genes by the expression of GABRD genes and 44 marker genes of three types of RNA modifications (m1A (10), m5C (13), m6A (21)) genes in pan-cancer, as shown in Figure 6 with a high correlation, especially higher in COAD and COADREAD tumors (P < 0.05). The gene discussed is GABRD; the disease is cancer.