Densitometric analysis revealed the decreased expression levels of NF-κB/p65, COX-2, p110a, CyclinD1, VEGF, AKT, T-mTOR, Ser2448p mTOR, and Bcl-2 after treatment with CZE and CIN, in both SCC-9 and SCC-25 cells. Here, AKT1 is linked to cervical squamous intraepithelial neoplasia.