Finally, we elucidated the underlying molecular mechanisms that might be responsible for these effects by finding out the significant binding protein and then studying the alteration in expression of different proteins that are involved in apoptosis (NF-kB and P53), cell cycle (Cyclin D1) and angiogenesis (Vascular endothelial growth factor, VEGF) leading to tumor spread and establishment. The gene discussed is TP53; the disease is neoplasm.