The top 10 significantly enriched GO terms in BP, CC and MF are plotted in Figure 3A, and the results showed that ASP’s effects might be mediated through response to wounding, response to drug, membrane raft, perinuclear region of cytoplasm, organelle outer membrane, transcription factor binding, protein kinase binding, and protein domain specific binding, to regulate the proliferation and apoptosis of CRC cancer cells, thus exerting its anti-cancer effects on CRC. The gene discussed is WEE1; the disease is cancer.