Of the three AD pathologies probed by PET imaging, Tau deposition (by AV-1451) appears to reveal the most relevant pathways related to AD, as well as including “Alzheimer’s disease” itself as the most highly significant BioPlanet-identified pathway via NDUFS4 & 8, NDUFA6 & 7 and UQCRQ. The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.