In addition, KEGG enrichment uncovered that HIF1A-regulated genes were involved in the “cancer pathway,” “HIF1 signaling pathway,” “PI3K-Akt signaling pathway,” “cancer,” “microRNAs in cancer,” and “P53 signaling pathway.” Furthermore, GO analysis revealed that HIF1A-regulated DEGs were mainly enriched in biological metabolic processes, cell membrane components, catalytic factor activity, transcription factor activity, and other cellular and biological functions (Figure 3C). This evidence concerns the gene TP53 and cancer.