IL1B and acute respiratory distress syndrome: Cytokine storm (CS) refers to a series of clinical disorders caused by immune response disorders (Kim et al., 2021), such as inflammatory lung injury and ARDS (Li et al., 2020b), accompanied by the rapid production of large amounts of cytokines (IL-1β, IL-1RA, IL-7, IL-8, IL-10, IFN-γ, and TNF-α) (Figure 2).