TNF and COVID-19: reported early cytokines that may predict disease outcome, including eotaxin 3, IL-33, Thymic Stromal Lymphopoietin, IL-21, IL-23, IL-17F, IFN-γ, IL- 12 p70, IL-15, IL-2, TNF, IL-4, IL-5, IL-13, IL-1α, IL-1β, IL-17A, IL-17E, IL-22 and many chemokines involved in leukocyte trafficking, these markers are associated with coagulation dysfunction and higher mortality in COVID-19 patients (Lucas et al., 2020).