WWTR1 and cancer: Moreover, as hyperactive YAP/TAZ leads to uncontrolled cell growth, a growing interest has been raised in the roles of YAP/TAZ in cancer progression (Saucedo and Edgar, 2007; Xu et al., 2009; Pan, 2010; Johnson and Halder, 2014; Mo et al., 2014; Lee Y. A. et al., 2018).