From the 1228 fine-mapped T1D-associated SNPs, we identified 36 variants that meet our filtering criteria: a variant must be in open chromatin region, where the chosen Hi-C interactions are contacting, overlapping with either a promoter or an enhancer region and bound by FOXP3 binding sties, in this study we will refer to them as T1D 3DFAACTS SNPs. The gene discussed is FOXP3; the disease is type 1 diabetes mellitus.