PFKFB3 and type 1 diabetes mellitus: When compared with the 36 variants identified from our T1D dataset analysis, two variants, rs61839660 on chromosome 10 and rs3087243 on chromosome 2 were also prioritised by 3DFAACTS-SNP analysis of the 5ID and 4AI datasets, respectively, implicating their interacting genes IL2RA, RBM17, PFKFB3 and LINC02649 (rs61839660), RAPH1 (rs3087243) are functionally implicated in the development of these diseases.