Similarly, a past large sample study found less than 35 g/L of serum albumin level was significantly associated with increased 30-day mortality for “borderline resectable type C” patients (defined as age ≥ 80, poor performance status, weight loss > 10%, pulmonary disease, recent myocardial infarction/angina, stroke history, and/or preoperative sepsis) who underwent PD, while association was not observed after adjusting confounding factors [25]. The gene discussed is ALB; the disease is angina pectoris.