FADS1 and metabolic syndrome: In a recent cross-sectional genome wide association study (GWAS) on Korean population, Park et al. revealed statistically significant interactions between total fat intake and the FADS1 rs174547 and haplotype of FADS1 rs174547 and FADS2 rs2845573 on MetS risk and it seemed that intermediate fat intake protected carriers of the FADS1 major alleles against the risk of MetS [58].