Finally, to validate the prevalence of the positive correlation between YAP1 and TIAM1 in clinical specimens, we performed gene correlation analysis based on 107 breast cancer patients in Auckland (GSE36771) and 1097 breast cancer patients from TCGA and found that TIAM1 expression was positively correlated with YAP1 (n = 107, R = 0.408, p < 0.001 in Auckland and n = 1097, R = 0.177, p < 0.001 in TCGA) (Fig. 5L). This evidence concerns the gene YAP1 and breast cancer.