In genomics data from The Cancer Genome Atlas (TCGA) via UALCAN (http://ualcan.path.uab.edu/)48, PLK1 expression increases with the elevation of pancreatic adenocarcinoma histological grade, and high PLK1 expression is a significant factor for poor prognosis in the overall survival (OS) of patients with pancreatic adenocarcinoma (Fig. 2a,b). Here, PLK1 is linked to pancreatic adenocarcinoma.