After the treatment of CML CD34+ cells with 100 nM Meds433 for 3 days, we found a significant increase in CD11c, OSCAR, CD1c (markers of dendritic cell and monocyte lineage), CD318 (a marker of cell migration), and CD61, CD41 (megakaryocytic markers) (Fig. 5A). Here, CD34 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.