ITGB3 and chronic myelogenous leukemia, BCR-ABL1 positive: After the treatment of CML CD34+ cells with 100 nM Meds433 for 3 days, we found a significant increase in CD11c, OSCAR, CD1c (markers of dendritic cell and monocyte lineage), CD318 (a marker of cell migration), and CD61, CD41 (megakaryocytic markers) (Fig. 5A).