After the treatment of CML CD34+ cells with 100 nM Meds433 for 3 days, we found a significant increase in CD11c, OSCAR, CD1c (markers of dendritic cell and monocyte lineage), CD318 (a marker of cell migration), and CD61, CD41 (megakaryocytic markers) (Fig. 5A). This evidence concerns the gene OSCAR and chronic myelogenous leukemia, BCR-ABL1 positive.