Frequencies of NKG2A(+) and NKG2C(+) NK-cell subpopulations were also comparable between the different cohorts (except for newly diagnosed ALL patients, P value <0.0001) with a majority of patient being NKG2A>C (92% of patients observed across diagnostic, complete remission and relapse/refractory status were NKG2A>C; Fig. 5b, middle and right panels). Here, KLRC1 is linked to acute lymphoblastic leukemia.