SERPINA1 and COVID-19: This analysis showed evidence of a shared genetic effect between protein levels of ENTPD5 (colocalization posterior probability [PP]=99.9%), OAS1 (PP=95.8%), FCRL3 (PP=100%), ICAM5 (PP=78.1%) and ICAM1 (PP=91.8%) with COVID-19 severity in European ancestry, and weaker evidence of a shared effect of protein level of SERPINA1 with COVID-19 severity in African ancestry (PP=64.3%) (Figure 3 and Table S11A).