One protein, ICAM1 showed suggestive effect on COVID-19 severity in both ancestries (OR in Europeans=1.152, 95%CI=1.063 to 1.249, P = 5.94 × 10−4; OR in Africans=1.481, 95%CI=1.008 to 2.176; P = 0.045). This evidence concerns the gene ICAM1 and COVID-19.