The colocalization analysis further suggested that splicing events of OAS1 and ICAM1 in adipose tissues showed some evidence of colocalization with COVID-19 severity (colocalization probability=92%∼98%; Table S13B), which further strengthens the putative causal role of OAS1 and ICAM1 on COVID-19 severity via alternative splicing events. The gene discussed is ICAM1; the disease is COVID-19.