GATA1 and dengue disease: Though, variant S129N was predicted to be neutral in different in silico approaches but patients harboring S129N mutation had a significantly (p = 0.02) lower platelet count (35.08±4.15 Kcells/μL) compared to the platelets of patients (60.65±4.14 Kcells/μL) carrying wild-type nucleotide as that present in the reference sequence of GATA1 (NC_000023.11) and same result was observed even after adjusting age and dengue fever type (Table 4).