This is in agreement with previous findings demonstrating that UCP2 is merely found in highly proliferating cells that have a glycolytic and anabolic metabolism, such as cancer and stem cells (19, 26–28), that can shut off mitochondrial respiration by upregulating UCP2, thereby inducing the Warburg effect and enhancing glucose metabolism and lactate production, even in the presence of oxygen (29). Here, UCP2 is linked to cancer.