NPM1 and acute myeloid leukemia: For convenience in following studies, the AML patients with NPM1 mutations were divided into two subgroups in the TCGA dataset, namely NPM1_Group1 whose territory bias to FAB_M5, and NPM1_Group2 whose territory bias to FAB_M2 (Fig. 2B; n = 17, 21 for NPM1_Group1 and Group2 respectively).