CDKN2A and hepatocellular carcinoma: CDKN2A was overexpressed in HCC versus normal tissue in two datasets, with a fold-change of 4.276 and P-value of 6.59 × 10−12 for Wurmbach et al.’s dataset [19], and a fold-change of 2.347 and P-value of 2.17 × 10−40 for Roessler et al.’s dataset (Table 1) [20].