Cytokine mRNA measurements in the site of infection, dLN, and spleen evidenced the expression of IFNγ, IL-10, IL-4, IL-12, and TGFβ (Travi et al., 2002; Osorio et al., 2003; Espitia et al., 2010), which resembles the mixed Th1/Th2/regulatory profile observed in humans (Bosque et al., 2000; Trujillo et al., 2002; Castilho et al., 2010; Díaz et al., 2010). This evidence concerns the gene IL4 and infection.