Alternative splicing events with high E(PSI) included the ADD3 exon 16, missplicing of which was reported in DM1 heart,7 in addition to newly identified missplicing events, such as LMO7 exon 39 and RABGAP1 exon 19 (Table 2 and Supplementary Fig. 8B). This evidence concerns the gene LMO7 and myotonic dystrophy type 1.