NFE2L2 and posterior cortical atrophy: Very interestingly, we found that NRF2 was highly expressed in mCRPC samples compared to HSPC samples, which were higher in 43 CRPC and 10 SCC samples compared to untreated PCa samples and were significantly suppressed after neoadjuvant endocrine therapy and lower in 84 neoadjuvant endocrine therapy (NHT) PCa samples.