NFE2L2 and posterior cortical atrophy: Interestingly, NRF2 levels were significantly suppressed after neoadjuvant endocrine therapy and lower in 84 neoadjuvant endocrine therapy (NHT) PCa samples and 54 neoadjuvant endocrine + neoadjuvant chemotherapy (NCHT) PCa samples compared to 281 untreated PCa samples (Figure 4(b)).