CXCR3 and neoplasm: CXCL9, CXCL10, and CXCL11/CXCR3 are anti-tumor angiogenic factors, and the inhibition of tumor angiogenesis can be achieved via upregulating the expression of CXCL9, CXCL10, and CXCL11 (Billottet et al., 2013).