The mammalian target of rapamycin (mTOR), a large serine/threonine protein kinase, plays a vital role in cell growth, proliferation, survival, nutrient metabolism, autophagy, and protein translation, at present, great endeavor has been made to transfer targeting mTOR for cancer to CNS diseases and the extensive role of mTOR has attracted much interest in this field (Park et al., 2008; Guo and Yu, 2019). The gene discussed is MTOR; the disease is cancer.