Previously, NF-κB was found to be constitutively activated in many cancers, and it promotes the survival, proliferation, and metastasis of tumor cells by increasing the expression of anti-apoptotic genes, cell cycle proteins, MMPs, cell adhesion genes, and angiogenesis-promoting genes (Li et al., 2015; Patel et al., 2018). The gene discussed is NFKB1; the disease is cancer.