Allicin has been found to decrease the levels of cytoplasmic P53, Bcl-2, and the PI3K/mTOR signaling pathway and to increase the expression of the AMPK/TSC2 and Beclin-1 signaling pathways in HepG2 cells, which can also induce the degradation of mitochondria in cancer cells, therefore, allicin promote the autophagy of cancer cells (Chu et al., 2012). This evidence concerns the gene BECN1 and cancer.