Every histone plays its own role: H2A-W6U132 could be involved in the expression of ATP binding cassette transporter A1 for drug resistance, H2A-W6U0N3 could be involved in cyst sterilization, H4-W6ULY2 could be involved in parasite life span, and H2A-W6UJM4 could be involved in embryonic proliferation. The gene discussed is ABCA1; the disease is cyst.