The HLA-DQB1*06:09 and HLA-DPA1/DPB1 alleles which we reported here, have been detected to be associated with chronic hepatitis B with similar tendencies in previous reports in different ethnic groups (Cho et al., 2008; Kamatani et al., 2009; Hu et al., 2013; Nishida et al., 2014, 2015, 2016; Li Y. et al., 2016; Zhu et al., 2016; Ou et al., 2019, 2021; Huang et al., 2020). The gene discussed is HLA-DQB1; the disease is chronic hepatitis B virus infection.