APP and amyotrophic lateral sclerosis: This effect, discovered long ago for synuclein which forms the Levy’s bodies typical of Parkinson’s disorder (Goedert et al., 2017), has been observed for most other cases including, for example, the amyloid precursor protein (APP) involved in Alzheimer’s and superoxide dismutase (SOD) involved in a quota of amyotrophic lateral sclerosis (ALS) (Morrison and Morrison 1999; Nordlund and Oliveberg 2006).