Of these, eleven differentially expressed lncRNAs have been found in human bio-samples (including whole blood, serum, sputum, and lung tissue samples) from COPD patients: NNT-AS1 (Mei et al., 2020), MEG3 (Lei et al., 2021), LUCAT1 (Zhao et al., 2021), SNHG5 (Shen et al., 2020), CASC2 (Liu et al., 2021a), TUG1 (Gu et al., 2019), OIP5-AS1 (Hao et al., 2021), LOC729178 (Wang et al., 2021), XIST (Chen et al., 2021), LINC00612 (Luo et al., 2020), and MIR155HG (Song et al., 2020). The gene discussed is TUG1; the disease is chronic obstructive pulmonary disease.