Zhao et al. (Zhao et al., 2021) detected the expression of lncRNAs in the serum from patients with COPD and found that the expression of lung cancer-associated transcript 1 (LUCAT1) was significantly increased, especially in the smoker COPD group, and LUCAT1 levels were positively correlated with inflammatory cytokine (IL-1β, IL-6, and TNF-α) expression in COPD patients. Here, IL6 is linked to chronic obstructive pulmonary disease.