There was a significant difference in plasma CXCL14 level among different histology subtypes (adenocarcinoma: 1647.88 pg/ml, squamous cell carcinoma: 2012.00 pg/ml, SCLC: 2886.00 pg/ml, other malignant types: 2776.21 pg/ml, P=0.009). The gene discussed is CXCL14; the disease is small cell lung carcinoma.