CXCL14 and lung cancer: ROC curve analysis showed that urine CXCL14 achieved an AUC of 0.647 (95% confidence interval [CI], 0.5829–0.7111) at a cutoff point of 888.7 pg/ml for diagnosis of stage I lung cancer, with 39.24% sensitivity and 90.16% specificity (Figure 3D).