There was no significant difference in urine CXCL14 level among different histology subtypes (adenocarcinoma: 516.78 pg/ml, squamous cell carcinoma: 569.22 pg/ml, SCLC: 1624.59 pg/ml, other malignant types: 580.77 pg/ml, P=0.691), smoking history (nonsmokers: 627.68 pg/ml, smokers: 485.40 pg/ml, P=0.574) (Table S3), or urine CXCL14 level among different stages (stage I: 506.23 pg/ml, stage II: 629.87 pg/ml, stage III: 569.22 pg/ml, stage IV: 346.12 pg/ml, P=0.389). Here, CXCL14 is linked to adenocarcinoma.