However, it is not only one connection with metabolic syndrome components, as MMP-1 serum levels are associated with atherosclerotic total plaque burden (46), and its production can be intensified in macrophages during dysglycemia (48) or elevated in plasma in case of hypertriglyceridemia as well as in CRP increase (49). The gene discussed is MMP1; the disease is hypertriglyceridemia.