In the highest uric acid quartile, the OR was 2.91 (95% CI: 1.54–5.51, P = 0.003 for trend) for MetS after further adjusting for alcohol drinking, smoking, duration of diabetes, self-reported CVD, BMI, CRP, HbA1C, FBG, eGFR, TC, and LDL-C. This evidence concerns the gene CRP and diabetes mellitus.