As depicted in Fig. 1A, levels of calprotectin were elevated in patients in remission with MPA (p<0.0001), GPA (p<0.0001), GCA (p<0.0001), and TAK (p=0.0004), as compared to healthy individuals, with 20–32% of the patients having highly elevated levels of calprotectin, as determined by the 95th percentile of healthy individuals. The gene discussed is GYPA; the disease is temporal arteritis.