ATP2B4 and malaria: PMCA4 is coded for by the Atp2b4 gene located on chromosome 1 (Iq32) and several single nucleotide polymorphisms (SNPs), namely rs10900585; rs1541254; rs1541255; and rs4951074, have been implicated in susceptibility to severe malaria in genome wide association [4] and epidemiologic studies in Africa and Oceania [19, 20].