ADAR and neoplasm: However, although there was a significant correlation between the ATIRE risk score and ADAR1 expression in TCGA-LUSC tumor tissues (Supplementary Figure S4), ADAR1 did not improve the performance of the established nomogram with similar Harrell’s C-indexes in both the training (i.e., 0.810) and validation (i.e., 0.665) sets.