Further, diverse complement proteins, including MBL [16–18], C3 [19], C1q-adiponectin [2], membrane attack complex (MAC) [19], complement factor H (CFH) [20] and complement receptor 1 (CR1) [21] were confirmed as significant predictors for the incidence of cardiovascular events or death for HD patients. The gene discussed is CR1; the disease is Huntington disease.