In fact, Abumrad et al.44 showed that CD36-deficient mice had an impairment in learning ability; from the perspective of the recent molecular studies mentioned above42,43,45 (for a review see20) such findings could be taken as an early hint that changes in the expression of CD36 may, indeed, contribute to the pathophysiology of dementia, including that of AD. The gene discussed is CD36; the disease is Alzheimer disease.