Although there were variations in TAGLN expression among biological replicates, which correlated well with GDM severity in the patient population (Supplementary Table 1), western blot analysis revealed that protein expression of TAGLN was significantly lower for GDM-ECFCs conjugated with SB-NPs compared to Vh-NPs controls (Fig. 3e and Supplementary Table 2). The gene discussed is TAGLN; the disease is gestational diabetes.