One interesting candidate for additional study would be tumour necrosis factor-alpha biology given elevated TNFRSF1A has also been associated with schizophrenia, bipolar disorder, and autism in the large post-mortem brain expression study from the PsychENCODE consortium64, although genetic evidence from GWAS for this gene is still lacking in the context of psychiatric phenotypes. This evidence concerns the gene TNFRSF1A and schizophrenia.