We recently generated ACE2-CAR NK cells that target the spike protein of SARS-CoV-2, and tested them in the K18-hACE2 animal model.286 Also, NK cells co-expressing NKG2D- and ACE2-CAR have been designed to treat patients with COVID-19, an infectious disease caused by SARS-CoV-2 (NCT04324996). The gene discussed is ACE2; the disease is COVID-19.