ASXL3 and Cowden disease: Because CD is an emerging infectious disease that is difficult to eradicate with antibiotics or pesticides, the best intervention strategy would be the development of a vaccine based on proteins such as flagellin, Brps (Bartonella repeat proteins), IalB (invasion-associated locus B protein), FtsZ, Hbp/Pap31 (hemon-binding proteins), the α-subunit of succinyl-CoA synthetase (SCS-α), GroEL and the β-subunit of succinyl-CoA synthetase (SCS-β), among others 4,7,9,10,.26