For example, CDCA5, ANLN, ASPM, KIAA0101, CENPF, FOXM1, PRC1, RACGAP1, TPX2, MELK, NDC80, and SPAG5 were predicted by WGCNA to be related to the tumor grade and prognosis in ACC [21]. The gene discussed is MELK; the disease is adrenal cortex carcinoma.