As shown in Figure 2, highly expressed HMGB1 was significantly associated with Overall Survival (OS) for cancers of ACC (p = 0.004), ESCA (p = 0.028), KICH (p = 0.037), KIRC (p = 0.045), LUAD (p = 0.009), PAAD (p = 0.026) and THYM (p = 0.035). Here, HMGB1 is linked to cancer.