VEGFA and Cystoid macular dystrophy: Cataract surgery is the most commonly performed surgical procedure in the world.[1] Posterior capsular opacification (PCO) can occur a few months to many years after uncomplicated clear corneal phacoemulsification with intraocular lens implantation, demanding further treatment with neodymium-doped yttrium aluminum (Nd:YAG)-laser capsulotomy.[2] In some operated eyes, removal of cataract can also cause postoperative cystoid macular edema (CME), leading to the need for intravitreal anti-vascular endothelial growth factor (VEGF) treatment.[3,4]