SND1 is a novel transcriptional coactivator that activates downstream Ras Homolog Family Member A (RhoA) transcription, sequentially regulates expression of Cyclin D1 (CCND1), Cyclin E1 (CCNE1) and Cyclin Dependent Kinase 4 (CDK4), and accelerates cell proliferation in GBM [48, 49]. Here, SND1 is linked to glioblastoma.