Moreover, the virus also decreased GA-MSC-mediated PD-L1 in human glioma cells U251 (P < 0.001, 41.83 ± 1.582 vs. 30.63 ± 0.834), U87 (P < 0.001, 68.17 ± 4.055 vs. 36.6 ± 3.736) and BT-01 (P < 0.001, 47.67 ± 1.818 vs. 15.83 ± 2.579) (Fig. 6C–H). The gene discussed is CD274; the disease is central nervous system cancer.