Moreover, owing to the high prevalence of Alzheimer’s dementia [193], pharmacological management of dementia (using acetylcholinesterase inhibitors, N-methyl-d-aspartate [NMDA] receptor antagonists, and combination treatment) is primarily focused on Alzheimer’s dementia, and this approach may be ineffective in treating or delaying symptoms of other types of dementia. The gene discussed is ACHE; the disease is dementia.