To further examine the distribution of 5hmC with other epigenetic marks in patients with myeloid neoplasms, we analyzed the 5hmC enrichment profile within the published DNase I hypersensitive site and histone modification (H3K4me1 and H3K27ac) regions collected from human CD34 + cells (Fig. 1F, Additional file 1: Table S2). This evidence concerns the gene CD34 and myeloid neoplasm.